Andreessen Horowitz (a16z) has formally requested the Commodity Futures Trading Commission (CFTC) to revise its rules on prediction-market event contracts. In a comment filed on April 30, 2026, a16z urged the CFTC to replace blanket prohibitions under Rule 40.11 with case-by-case public interest determinations. The firm also called for coordinated oversight with the SEC, leveraging their recent memorandum of understanding. a16z's filing highlights the rapid growth of prediction markets, citing Kalshi's weekly trading volume increase from $300 million to $3 billion. The firm argues that current regulations are outdated and that clearer rules could resolve jurisdictional conflicts, such as the ongoing federal lawsuit against Arizona, Connecticut, and Illinois over state regulation of prediction markets. The CFTC's decision could significantly impact the legal landscape for these markets.