The University of Chicago has refuted claims of losing over $6 billion in cryptocurrency investments, as suggested by Professor Zhao Dingxin. According to the university's official statement, their cryptocurrency investments are relatively small and have more than doubled over the past five years, contradicting reports of significant losses. Financial records indicate that the university's cryptocurrency holdings decreased from $64 million in 2021 to $45 million in 2022, marking a $19 million loss. However, the university maintains a cautious investment approach, and its overall endowment has not suffered from such drastic losses. The institution's financial challenges are attributed to strategic miscalculations and high debt levels, rather than cryptocurrency trading.