Jerome Powell's recent speech led to over $374 million in cryptocurrency liquidations within 12 hours, impacting Bitcoin, Ethereum, and other major altcoins. The sharp market reaction underscores the crypto market's sensitivity to Federal Reserve policy signals. Exchange and aggregator dashboards recorded significant drops, while futures markets experienced heightened volatility as traders swiftly responded to Powell's comments. This event highlights the ongoing influence of central bank communications on digital asset price movements.