Celo, Raydium, Ethena, CurveDAO, and Uniswap are identified as altcoins with strong breakout potential this December. These cryptocurrencies exhibit robust on-chain metrics, such as increased transaction throughput and liquidity depth. Technical indicators, including falling wedges and trendline bounces, further support the likelihood of upward momentum. Historical performance and current protocol activity suggest these altcoins may experience significant gains in the coming weeks.