Ethereum's recent price pullback has led to negative unrealized profit margins for major ETH holders, according to CryptoQuant analyst Darkfost. Whales holding between 1,000 and 10,000 ETH now face a margin of -0.21, those with 10,000 to 100,000 ETH are at -0.18, and holders of over 100,000 ETH are at -0.08. If Ethereum's price continues to decline, these large holders may encounter increased financial pressure.