In September 2025, Ethereum, Solana, Dogecoin, XRP, and Little Pepe (LILPEPE) have emerged as the top cryptocurrencies favored by large investors. Ethereum is trading near $4,400, with expectations of reaching $7,500 by the end of the year. Solana continues its upward trend, trading around $210, while Dogecoin remains steady at approximately $0.217. XRP benefits from institutional support, trading near $2.81. Little Pepe (LILPEPE) has captured attention with a successful presale, raising $24.6 million, and plans for exchange listings. The LILPEPE chain aims to be the exclusive Layer 2 solution for meme coins, offering enhanced speed and cost efficiency. This trend underscores the significant interest from whales in these cryptocurrencies, marking them as pivotal in the current market cycle.