Cryptocurrency markets declined on August 21, 2025, as investors responded to the Federal Reserve's latest minutes and looked ahead to the Jackson Hole Symposium. Bitcoin fell 0.4% to $112,773, while Ethereum decreased by 0.7% to $4,242, contributing to a 1% drop in overall market capitalization to $3.9 trillion. The cautious market sentiment was driven by the Fed's July minutes, which highlighted concerns over inflation and employment risks. Despite some Fed Governors advocating for rate cuts, the decision was made to maintain interest rates between 4.25% and 4.5%. Investors are now keenly awaiting Fed Chair Jerome Powell's upcoming remarks, which could further impact crypto market trends. Spot Bitcoin and Ethereum ETFs saw notable outflows, underscoring the market's cautious approach.