Coinbase has launched Prediction Markets across all 50 U.S. states, utilizing technology from Kalshi. This development marks a significant expansion in the use of Web3 markets, which are increasingly seen as a source of alpha rather than a mere curiosity. These markets allow participants to engage in real-time pricing of events such as Federal Reserve policy outcomes, regulatory changes, and geopolitical developments. The introduction of Prediction Markets by Coinbase is expected to attract substantial interest, with projections of hundreds of millions, potentially billions, in open interest on key macroeconomic themes. This move highlights the growing importance of Web3 markets in providing new opportunities for diversification, signal weighting, and event-risk hedging, making them a focal point for institutional investors.