Consensus 2026 will explore the transformative impact of AI agents and blockchain payments on commerce, as over 15,000 leaders from crypto, AI, and finance sectors gather in Miami Beach from May 5 to 7. AI agents, capable of autonomous transactions, are set to redefine payment systems, challenging traditional methods like credit cards and bank logins. Key discussions will focus on infrastructure, regulatory frameworks, and business models needed to support this shift. Prominent figures such as Yat Siu of Animoca and Christian Catalini of MIT will address the challenges and opportunities of integrating AI with blockchain. Google Cloud's Rich Widmann highlights the need for agent-specific payment infrastructure, with protocols like x402 and MPP emerging as potential solutions. The event will also feature CoinDesk University, offering practical courses on deploying agent payment systems, underscoring the urgency of adapting to this rapidly evolving landscape.