Wells Fargo has launched Bitcoin-backed loans for institutional and high-net-worth clients, marking a significant step in integrating cryptocurrency into traditional finance. This move highlights the growing acceptance of Bitcoin as collateral among major financial institutions in the United States. The bank's new offering, confirmed by MicroStrategy's Michael Saylor, includes interest rates ranging from 4% to 6% and loan-to-value (LTV) ratios between 50% and 70%. This development reflects a broader trend among major U.S. banks, including Citibank, Bank of America, and JPMorgan, which are also providing similar crypto-backed credit lines. The introduction of Bitcoin-backed lending by Wells Fargo underscores shifting attitudes in financial markets, driven by increasing client demand for cryptocurrency-backed products. This could potentially enhance Bitcoin's role in mainstream finance and encourage further integration of digital assets within regulated financial frameworks.