Bitcoin's institutional demand has sharply declined in 2025, with inflows to BlackRock's spot BTC ETF dropping from over 10,000 BTC per week to less than 1,000 BTC. On-chain data from Glassnode and CryptoQuant indicates a significant reduction in buying pressure, with negative demand patterns reminiscent of previous local market bottoms. Overall, ETF inflows for major funds have decreased by 90%, and Bitcoin treasury firms have reduced their aggressive purchasing strategies. This trend suggests potential continued downward pressure on Bitcoin prices unless institutional interest revives.