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Top DeSci Projects in 2024

Author: Kenny Date: 2024-05-11 21:13:11

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What is DeSci?

Decentralized Science (DeSci) represents a paradigm shift in how scientific research is conducted, using Web3 and blockchain technologies to democratize and decentralize the scientific process. Traditionally, scientific endeavors have been tightly controlled by institutions and gatekeepers, such as academic journals and funding bodies, which can limit innovation and access to research. DeSci aims to remove these barriers by utilizing decentralized networks that allow for open collaboration, transparent peer review, and equitable distribution of funding through mechanisms like smart contracts and decentralized autonomous organizations (DAOs).

How Does DeSci Work?

DeSci leverages blockchain technology to create a more open and accessible scientific ecosystem. In this model, scientific data and research outputs are stored on a decentralized ledger, ensuring integrity, immutability, and accessibility. This setup facilitates global collaboration among scientists without the need for intermediaries. Moreover, DeSci employs smart contracts to manage intellectual property rights and research funding transparently and efficiently. These contracts can automatically execute transactions and distribute funds based on pre-defined criteria and milestones, reducing the administrative overhead and bias typically associated with research funding.

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Top DeSci Projects in 2024

Here are some of the top decentralized science (DeSci) projects that have been making significant impacts in 2024:


  • Description: Uses blockchain technology to create a transparent and accessible ecosystem for scientific research, enhancing the integrity and provenance of scientific data.
  • Unique Features: Promotes open access to research outputs and encourages cross-disciplinary collaborations, effectively democratizing the scientific discovery process.


  • Description: A decentralized platform that aims to transform the scientific experimentation process by enabling global collaborations and the sharing of results in a decentralized network.
  • Unique Features: Allows researchers to conduct and replicate experiments in a trustless environment, promoting transparency and reproducibility.


  • Description: A decentralized marketplace that bridges the gap between scientific researchers and funding sources by facilitating the tokenization of intellectual property related to innovative research projects.
  • Unique Features: Simplifies the transaction and investment processes, making it easier for researchers to secure funding and for investors to gain stakes in scientific discoveries.


  • Description: A community-driven platform aimed at democratizing access to scientific equipment and laboratory services.
  • Unique Features: Utilizes a membership model where tokens represent access rights to equipment and services, fostering a collaborative environment where resources are shared and managed by the community of users.


  • Description: Focused on making the scientific publishing process more transparent and accessible by reducing the barriers often associated with traditional publishing houses.
  • Unique Features: Uses blockchain to log all peer review activities, ensuring the integrity and verifiability of the review process, making scientific publications more reliable and widely accessible without high fees.

Chainlink Science

  • Description: Uses oracle technology to securely and reliably integrate off-chain data into blockchain-based scientific research projects, expanding the types of data available for scientific inquiries.
  • Unique Features: Enables real-world data to be utilized in decentralized applications, thereby broadening the scope and utility of blockchain in various scientific fields.

OriginTrail (TRAC)

  • Description: Described as a "decentralized knowledge graph" that is used to find, handle, and store data for various applications such as supply chain tracing, certificate verification, art, and diploma verification.
  • Unique Features: Utilizes blockchain and knowledge graph technology to facilitate AI-ready knowledge assets and covers network costs with TRAC tokens.

Hippocrat (HPO)

  • Description: A blockchain-based decentralized patient network that helps patients manage their health data and engage with communities for support and information.
  • Unique Features: Provides a protocol for data exchange that ensures compensation for all parties involved in data creation and processing, enhancing transparency and security.


  • Description: Focused on longevity research, funding projects that aim to extend human life through scientific discovery.
  • Unique Features: Operates through smart contracts on the Ethereum network, allowing community members to participate in governance decisions regarding the allocation of funds and research directions.

ResearchCoin (RSC)

  • Description: Supports the scientific community by allowing members to earn tokens through participation, curation, and collaboration on the ResearchHub platform.
  • Unique Features: The community can vote to change the tokenomics, which can adjust the supply and distribution of RSC based on community decisions.

Dynex (DNX)

  • Description: A peer-to-peer cryptocurrency that uses a Proof-of-Useful-Work (PoUW) mining algorithm to facilitate more meaningful and energy-efficient mining.
  • Unique Features: Designed to provide supercomputing capabilities by leveraging the collective power of participating miners, promoting advancements in fields like quantum computing.

AxonDAO Governance Token (AXGT)

  • Description: Allows token holders to vote on scientific research proposals that the DAO might fund, directly influencing the direction of supported research.
  • Unique Features: Transactions involving AXGT tokens contribute directly to a research fund, eliminating middlemen and fostering direct community involvement in funding decisions.


  • Description: Focuses on dermatology and hair care research, aiming to solve prominent issues in these fields through decentralized funding and community involvement.
  • Unique Features: Maintains a fully on-chain presence, with token holders able to inspect all assets managed by the DAO.

Galeon (GALEON)

  • Description: Offers a staking feature and operates within the healthcare sector, proposing a utility token for
  • Unique Features: It supports a systematic "buy-back and burn" strategy to manage token supply and value, enhancing token stability and investor confidence.

Why Consider DeSci Investments?

Investing in DeSci projects offers a unique opportunity to participate in the cutting-edge intersection of science and technology. These investments not only hold the potential for financial returns but also contribute to advancing scientific research and innovation. For investors, DeSci projects represent a chance to fund groundbreaking work in various scientific fields, from longevity and healthcare to environmental science, while benefiting from the inherent transparency and security offered by blockchain technology. Moreover, as DeSci continues to grow, the technologies and discoveries funded through these platforms could lead to significant societal benefits and commercial applications.

Benefits of DeSci

  1. Increased Transparency and Integrity: DeSci platforms use blockchain to ensure that all transactions, data exchanges, and publication processes are recorded immutably, making them transparent and resistant to tampering. This promotes trust in scientific findings and processes.
  2. Enhanced Collaboration: By removing geographical and institutional barriers, DeSci enables scientists from around the world to collaborate more freely. Blockchain networks facilitate the sharing of data and resources, making it easier and faster for researchers to build on each other's work.
  3. Democratized Access to Funding: Traditional funding mechanisms often favor established researchers and institutions, which can stifle innovation from less well-known entities. DeSci democratizes access to funds by using DAOs where members of the scientific community can vote on project funding, ensuring that more innovative but lesser-known projects have a chance to receive support.
  4. Streamlined Publication Processes: DeSci can significantly speed up the publication process by eliminating the lengthy peer review times associated with traditional scientific publishing. Platforms leveraging DeSci principles can facilitate rapid, open peer reviews, and immediate publication, accelerating the dissemination of new knowledge.
  5. Incentives for Reproducibility: Reproducibility is a major challenge in traditional science. DeSci platforms can offer incentives for replication studies through tokenization, rewarding researchers who verify or build upon existing studies, thereby improving the reliability of scientific research.
  6. Intellectual Property Management: Through smart contracts, DeSci platforms can manage intellectual property rights transparently and efficiently. Researchers can maintain control over their inventions and receive proper compensation when their work is used, reducing disputes and encouraging more open sharing of ideas.
  7. Reduced Publication Bias: Since DeSci systems are not driven by profit motives like traditional publishing houses, they can reduce biases related to publication. This allows more diverse research findings to be published, including negative results, which are often overlooked but crucial for scientific progress.


DeSci is not just a technological innovation; it is a comprehensive reimagining of the scientific research landscape. It offers a more transparent, collaborative, and equitable environment for scientific discovery, which could lead to faster advancements and more robust research outcomes. For crypto exchange platforms, promoting and integrating DeSci projects could attract a tech-savvy audience keen on supporting the intersection of science and blockchain technology, potentially leading to new opportunities for growth and innovation.

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